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Title:: Diagnostic value of high-resolution MRI combined with DWI in the differentiation of benign and malignant prostate lesions

Author(s):: HE Nan1; ZHANG Wei1; TANG Lusheng2; WANG YingXin1; 1. Department of Urology, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. School of Medical Imaging, Inspection and Rehabilitation, Xiangnan University, Chenzhou 423000, China

Keywords:: Keywords: prostate lesion differential diagnosis magnetic resonance imaging high resolution diffusion-weighted imaging

Abstract:: Abstract: Objective To explore the value of high-resolution magnetic resonance imaging (HR-MRI) combined with diffusion-weighted imaging (DWI) in the differential diagnosis of benign and malignant prostate lesions. Methods A retrospective analysis was performed on the clinical data of 108 patients with prostate lesions admitted to the Chenzhou No.1 Peoples Hospital. Patients were categorized into benign (n=57) and malignant (n=51) groups according to pathological results, and the diagnostic efficacy of HR-MRI combined with DWI was assessed for differentiating benign and malignant prostate lesions. Results No significant differences were observed in prostate volume between the two groups (P>0.05), but apparent diffusion coefficient in malignant group was lower than that in benign group (P<0.05). With pathological findings as the gold standard, the consistency Kappa values of HR-MRI, DWI, and their combination for distinguishing benign and malignant prostate lesions were 0.572, 0.684, and 0.833, respectively (P<0.05).The sensitivity and accuracy of HR-MRI combined with DWI in differentiating prostate lesions were 94.12% and 91.67%, higher than those of HR-MRI alone (76.47%, 78.90%) and DWI alone (82.35%, 84.26%) (P<0.05). Conclusion HR-MRI combined with DWI exhibit higher application value in the differential diagnosis of benign and malignant prostate lesions.