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Title:: Research status of in vivo dosimetric verification methods in radiotherapy

Author(s):: HE Yujia1; 2; 3; 4; ZHANG Yutao1; 2; 3; 4; XIE Kai1; 2; 3; 4; GAO Liugang1; 2; 3; 4; ZHANG Nan1; 2; 3; 4; ZHANG Ziteng1; 2; 3; 4; WANG Ziyi1; 2; 3; 4; HU Jing1; 2; 3; 4; NI Xinye1; 2; 3; 4; 1. The Third Affiliated Hospital of Nanjing Medical University (Changzhou Second Peoples Hospital), Changzhou 213003, China 2. Jiangsu Province Engineering Research Center of Medical Physics, Changzhou 213003, China 3. Center of Medical Physics, Nanjing Medical University, Changzhou 213003, China 4. Changzhou Key Laboratory of Medical Physics, Changzhou 213003, China

Keywords:: Keywords: radiotherapy log file electronic portal imaging device cone beam computed tomography in vivo dosimetric verification review

Abstract:: Abstract: Precision radiotherapy, as a pivotal modality in modern tumor treatment, strives to maximize tumor irradiation while minimizing damage to adjacent healthy tissues. In vivo dosimetric verification serves as a critical procedure for ensuring the quality and safety of precision radiotherapy, and plays a significant role in preventing radiation-induced injuries. Currently, in vivo dosimetric verification techniques in radiotherapy can be classified into two categories: those based on accelerator log files and those relying on accelerator imaging data. Herein this review systematically explores the fundamental principles and research advances of these two approaches, analyzes the existing challenges, and outlines future development directions, with the aim of providing more comprehensive theoretical support and practical reference for clinical practice.