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Title:: Preparation and properties of β-tricalcium phosphate/hydroxyapatite-based alveolar bone composite materials

Author(s):: QI Yan1; MA Lin2; FAN Jiang2; GONG Yi2; WANG Nanfei2; ZHANG Ting3; 1. Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China 2. Department of Orthopedics, Nanbu Peoples Hosipital, Nanchong 637399, China 3. Biomedical Engineering Teaching and Research Department, College of Health and Intelligent Engineering, Chengdu Medical College, Chengdu 610083, China

Keywords:: Keywords: β-tricalcium phosphate hydroxyapatite dental alveolar bone composite preparation process performance test

Abstract:: Abstract: Objective To prepare a composite material by combining β-tricalcium phosphate (β-TCP) and hydroxyapatite (HAP) for alveolar bone repair, and to investigate its properties. Methods β-TCP and HAP were fabricated individually via the hydrothermal synthesis, followed by compositing the two materials through calcination. The prepared alveolar bone composite was analyzed with XRD and SEM, and evaluated for hydrophilicity, porosity, mechanical properties, and cytotoxicity. Results Experimental results demonstrated that the alveolar bone composite prepared from β-TCP and HAP at a ratio of 5:5 exhibited better hydrophilicity, porosity, and mechanical properties than the composites with other ratios. Most importantly, this composite material showed low toxicity. Conclusion With further development, the composite materials of β-TCP and HAP is expected to achieve significant progress in the application of alveolar bone repair and filling.