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Proton beam range verification algorithm for pixelated prompt gamma-ray imaging detector(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2025年第3期
Page:
281-287
Research Field:
医学放射物理
Publishing date:

Info

Title:
Proton beam range verification algorithm for pixelated prompt gamma-ray imaging detector
Author(s):
YANG Liwang1 OU Haifeng1 WANG Jinlong2 WU Xiaoguang2 HE Ziyang2 ZOU Jian’an2 ZHENG Yun2 LI Congbo2 GUAN Shaoxiong2 SHI Jing2 LI Jinze2 LI Yunqiu2 HONG Rui2 CHANG Hao’en1 WANG Mengting1 WEI Kaijie1
1. School of Physics, Henan University of Technology, Zhengzhou 450001, China; 2. Nuclear Physics Institute, China Institute of Atomic Energy, Beijing 102413, China
Keywords:
prompt gamma proton therapy range verification pixelated
PACS:
R318R811
DOI:
10.3969/j.issn.1005-202X.2025.03.001
Abstract:
In proton therapy, prompt gamma-ray imaging is considered as one of the most promising methods for assessing proton beam range. Prompt gamma-ray imaging detector evaluates the proton beam range based on the prompt gamma-ray distribution obtained by the prompt gamma-ray imaging system, which enables high-precision measurement of the proton beam range. Herein a proton beam range verification algorithm is designed for the newly developed prototype of the range verification detector (pixelated prompt gamma-ray imaging detector), which verifies the range estimation accuracy of the prototype for different phantoms and different energies of homogeneous media through Monte Carlo simulation. The results show that the accuracy of the proton beam range verification algorithm is within 0.5 mm of the safety margin error of the Bragg peak, and the measurement accuracy is significantly improved with the increase of the number of protons, indicating that the prototype algorithm is feasible for proton beam range verification.

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Last Update: 2025-03-27