Development of a fast Monte Carlo dose verification module for helical tomotherapy(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2024年第11期
- Page:
- 1321-1326
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Development of a fast Monte Carlo dose verification module for helical tomotherapy
- Author(s):
- LI Shijun1; GAO Ning1; CHENG Bo1; PI Yifei2; WANG Haiyang1; 2; CHANG Yankui1; PEI Xi3; Xie George XU1; 4
- 1. School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China 2. Department of Radiotherapy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China 3. Anhui Wisdom Technology Co., Ltd., Hefei 238000, China 4. Department of Radiotherapy, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China
- Keywords:
- Keywords: helical tomotherapy Monte Carlo dose verification ArcherQA
- PACS:
- R318；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2024.11.001
- Abstract:
- Abstract: Objective To develop a GPU-based Monte Carlo dose calculation module for helical tomotherapy (TOMO), and integrate it into the commercial software ArcherQA to achieve fast and accurate dose verification in clinic. Methods The TOMO treatment head was modeled using TOPAS to obtain phase space files, and a fast weight tuning algorithm was used to simulate particle transport in multi-leaf collimator for improving computational efficiency, and finally, GPU-based Monte Carlo algorithms in ArcherQA were used to simulate particle transport in patients. To verify the model accuracy, the ArcherQA calculated results in water tank were compared with measured data for different open fields. In addition, multiple comparisons among ArcherQA results, TPS results and ArcCHECK results were conducted on 15 clinical cases (5 cases in the head and neck, 5 cases in the chest and abdomen, and 5 cases in the whole body). Results In the water tank tests for 40 cm×5.0 cm, 40 cm×2.5 cm and 40 cm×1.0 cm radiation fields, the average global relative errors of the percentage depth dose, transverse dose distribution, and longitudinal dose distribution calculated by ArcherQA with the corresponding measured values were 0.72%, 0.66%, and 0.54%, respectively. Over 98% of the voxels had a global relative error of less than 1%. As for 15 clinical cases, in 2%/2 mm criteria, the mean Gamma passing rate was 98.1% between ArcherQA and TPS, 99.1% between TPS and ArcCHECK, and 99.4% between ArcherQA and ArcCHECK. The uncertainty of the simulation maintained less than 1%, and the average time taken for calculation based on patient CT vs ArcCHECK phantom was 87 s vs 64 s. Conclusion ArcherQA can be used for independent dose validation for TOMO plans for it can provide fast and accurate dose calculations.
Last Update: 2024-11-26