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Diagnostic value of DCE-MRI and ADC value in benign and malignant breast non-mass-like enhancement lesions(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2023年第9期
Page:
1132-1134
Research Field:
医学影像物理
Publishing date:

Info

Title:
Diagnostic value of DCE-MRI and ADC value in benign and malignant breast non-mass-like enhancement lesions
Author(s):
XU Jing1 MA Guanghui2 MENG Kailong1 WANG Yonggang1 LIU Penghua1
1. CT Room, Handan First Hospital, Handan 056002, China 2. the Third Department of General Surgery, Handan First Hospital, Handan 056002, China
Keywords:
Keywords: dynamic contrast-enhanced magnetic resonance imaging apparent diffusion coefficient breast non-mass-like enhancement lesion differential diagnosis
PACS:
R737.9;R816.4
DOI:
DOI:10.3969/j.issn.1005-202X.2023.09.012
Abstract:
Abstract: Objective To investigate the clinical value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and apparent diffusion coefficient (ADC) value in the differential diagnosis of benign and malignant breast non-mass-like enhancement (NMLE) lesions. Methods A retrospective analysis was carried out on 180 patients with breast NMLE lesions who underwent surgery and histopathological diagnosis in Handan First Hospital. All patients were scanned by multimodal 3.0T MRI. The distribution types, enhancement characteristics, time-intensity curve (TIC) types and ADC values of benign and malignant lesions were compared and the efficiency of ADC value in the differential diagnosis of benign and malignant lesions was evaluated by receiver operating characteristic (ROC) curve. Results Compared with benign lesion group, malignant lesion group had higher proportions of segmental distribution, cluster like enhancement and ADC value ≤1.3×10-3 mm2/s, and lower ADC value (all P<0.05). There was no significant difference in TIC types between two groups (P>0.05). The ROC curve analysis showed that the AUC, sensitivity and specificity of ADC value in differentiating benign and malignant breast NMLE lesions were 0.73, 72.33% and 79.60%, respectively, with the best cut-off value of 1.3×10-3 mm2/s. Conclusion DCE-MRI and ADC value have clinical application value for they can effectively improve the diagnostic efficacy of benign and malignant breast NMLE lesions.

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Last Update: 2023-09-26