Application and evaluation of DIBH radiotherapy using RGSC for left-sided breast cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第8期
- Page:
- 933-937
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Application and evaluation of DIBH radiotherapy using RGSC for left-sided breast cancer
- Author(s):
- WEI Xiaping1; SU Jiehong1; LI Lin1; AN Shixia1; DONG Yanxin1; HUANG Xiaowei2; LIU Yeming1; HUANG Mingchao1
- 1. Department of Radiation Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510168, China 2. Department of Science and Technology, Dongguan University of Technology, Dongguan 523808, China
- Keywords:
- Keywords: breast cancer volumetric modulated arc therapy respiratory gating deep inspiration breath hold
- PACS:
- R815.6；R737.9
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.08.002
- Abstract:
- Abstract: Objective To evaluate the clinical value of RGSC-guided deep inspiration breath hold (DIBH) radiotherapy following surgery for left-sided breast cancer by analyzing the exposure doses to heart and lung, treatment duration, and positioning accuracy. Methods After surgery for left-sided breast cancer, 20 cases receiving RGSC-guided DIBH volumetric modulated arc therapy and 20 cases treated with FB radiotherapy were enrolled, and the target areas contained only the chest wall and the clavicle. The V20, Dmean of the heart, and the V20, V10, V5, Dmean of the lung were obtained the target registration results were analyzed and the duration of each treatment was recorded. Results The V20 and Dmean of the heart in DIBH radiotherapy and FB radiotherapy were 2.36%±2.16% vs 7.26%±3.66% (P<0.01), and (3.52±1.10) Gy vs (6.56±1.59) Gy (P<0.01). The V20, V10, V5 and Dmean of the left lung in the two groups were 18.56%±4.51% vs 23.51%±4.37% (P=0.03), 30.48%±4.99% vs 37.99%±5.13% (P<0.01), 45.95%±5.81% vs 52.08%±12.74% (P=0.02), (10.57±1.86) Gy vs (12.43±1.66) Gy (P=0.01), respectively. The V5 and Dmean of the right lung were 7.82%±3.59% vs 18.41%±11.44% (P<0.01) and (1.97±0.36) Gy vs (3.08±1.12) Gy (P<0.01). The duration of DIBH radiotherapy and FB radiotherapy were 181.00 (151.00, 229.00) s and 70.20 (69.60, 70.20) s (P<0.01). After six-dimensional registration of CBCT images, the registration errors of DIBH radiotherapy were less than those of FB radiotherapy in the X, Y, Z, Rx, Rz directions, but not in the Ry direction (P>0.05). Conclusion RGSC-guided DIBH radiotherapy following surgery for left-sided breast cancer can achieve higher treatment accuracy than FB therapy, and reduce the doses exposed to the lung and heart, but increases treatment duration.
Last Update: 2023-09-06