Correlations of amplitude-integrated electroencephalogram with radial artery blood gas analysis and cranial MRI in asphyxiated newborns(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第8期
- Page:
- 1020-1024
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Correlations of amplitude-integrated electroencephalogram with radial artery blood gas analysis and cranial MRI in asphyxiated newborns
- Author(s):
- ZENG Liming; HUANG Jun; YANG Qing
- Department of Pediatrics, Chaohu Hospital of Anhui Medical University, Hefei 238000, China
- Keywords:
- Keywords: neonatal asphyxia amplitude-integrated electroencephalogram radial artery arterial blood gas analysis magnetic resonance imaging
- PACS:
- R722.12
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.08.018
- Abstract:
- Abstract: Objective To investigate the correlations of amplitude-integrated electroencephalogram (aEEG) with radial artery blood gas analysis and cranial MRI in newborns with asphyxia. Methods The clinical data of 50 children with neonatal asphyxia were analyzed retrospectively. The correlations of different asphyxia degrees with the degree of aEEG abnormality, sleep-wake cycle and epileptiform activity were analyzed. In addition, the correlations of the degree of aEEG abnormality with the results of radial artery blood gas analysis and the degree of MRI abnormality were studied. Results The degree of asphyxia was positively correlated with the degree of aEEG abnormality, sleep-wake cycle and epileptiform activity (P<0.05). There were significant differences in pH, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2) and base excess (BE) between children with different degrees of aEEG abnormality (P<0.05). Compared with those in mild abnormal aEEG group, the PCO2 level in normal aEEG group was significantly lower (P<0.05), and the BE level was significantly higher (P<0.05). The pH, PO2 and BE levels in normal aEEG group and mild abnormal aEEG group were significantly higher than those in severe abnormal aEEG group, but the PCO2 level in severe abnormal aEEG group was significantly higher that in the other groups (P<0.05). There was a positive correlation between degree of aEEG abnormality and degree of MRI abnormality (P<0.05). Conclusion The aEEG examination result of asphyxiated newborns is closely related to the results of radial artery blood gas analysis and cranial MRI, and therefore can be used for the ultra-early diagnosis of asphyxia in newborns.
Last Update: 2022-09-05