Collateral circulation assessment in acute ischemic stroke based on low dose whole brain CT perfusion(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第8期
- Page:
- 950-956
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Collateral circulation assessment in acute ischemic stroke based on low dose whole brain CT perfusion
- Author(s):
- WANG Yannan1; 2; ZHOU Junlin1; 2; NA Feiyang3; LIU Xianwang1; 2; LIU Jianli1; 2
- 1. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730000, China 2. Key Laboratory of Medical Imaging in Gansu Province, Lanzhou 730000, China 3. Allergy Department, Gansu Provincial Maternity and Child-care Hospital, Lanzhou 730000, China
- Keywords:
- Keywords: low-dose whole brain CT perfusion stroke collateral circulation
- PACS:
- R743.3；R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.08.005
- Abstract:
- Abstract: Objective To investigate the role of optimized multiphase CT angiography (omCTA) based on volume reconstruction using low dose whole brain CT perfusion (CTP) data in the assessment of collateral circulation in patients with acute ischemic stroke. Methods A total of 56 patients with ischemic stroke who were diagnosed as having unilateral middle cerebral artery occlusion were admitted to Stroke Center of Lanzhou University Second Hospital from October 2019 to October 2021. After admission, all patients underwent multimodality CT (head plain scan + whole brain CTP + head and neck CTA) examination. The CTP original data and ASiR-V algorithms with different weights (40%, 60% and 80%) were used to reconstruct omCTA images. The CT number of vascular enhancement, signal-to-noise ratio, contrast-to-noise ratio, subjective image quality and collateral circulation score were compared between omCTA groups and CTA group. Results The effective radiation dose of low dose whole brain CTP was (2.27±0.10) mSv, and the total radiation dose of multimodality CT scan was (3.21±0.17) mSv.?here was no significant difference in the CT number of arterial enhancement among omCTA3 groups with 40%, 60% and 80% ASiR-V. The CT number of vascular enhancement in omCTA groups was higher than that in CTA group (P<0.05).?he differences in signal-to-noise ratio and contrast-to-noise ratio between omCTA groups and CTA group were trivial (P>0.05).?he omCTA images reconstructed with 60% ASIR-V in omCTA group were superior to those reconstructed in CTA group in arterial enhancement and venous contamination (P<0.05).?he image noises in omCTA groups were lower than those in CTA group, and the omCTA group with 60% ASir-V has the least noise.?onclusion The omCTA image obtained based on low dose CTP can be used to comprehensively assess collateral circulation status in patients with acute ischemic stroke.
Last Update: 2023-09-06