Application of ultrasound-guided quadratus lumborum block combined with propofol anesthesia in laparoscopic radical resection for colorectal cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第5期
- Page:
- 567-571
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application of ultrasound-guided quadratus lumborum block combined with propofol anesthesia in laparoscopic radical resection for colorectal cancer
- Author(s):
- LIN Shengmin1; CHEN Xiaoyun2
- 1. Department of Anesthesiology, the Second Nanning Peoples Hospital (the Third Hospital Affiliated to Guangxi Medical University), Nanning 530031, China 2. Department of Anesthesiology, Wuming Hospital Affiliated to Guangxi Medical University, Nanning 530199, China
- Keywords:
- Keywords: colorectal cancer laparoscopic radical resection ultrasound-guided quadratus lumborum block propofol
- PACS:
- R614
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.05.008
- Abstract:
- Abstract: Objective To explore the application value of ultrasound-guided quadratus lumborum block combined with propofol anesthesia in patients with colorectal cancer undergoing laparoscopic radical resection. Methods Ninety colorectal cancer patients scheduled for laparoscopic radical resection were enrolled as the study subjects, and they were randomly classified as observation group and control group, with 45 cases in each group. Control group was treated with traditional lumbar anesthesia combined with propofol anesthesia, while observation group was given ultrasound-guided quadratus lumborum block combined with propofol anesthesia. The systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) during surgery (at 5, 15, 30 and 60 min after anesthesia) were recorded. Moreover, pain score (VAS score) at different time points after surgery as well as addition of analgesics and postoperative intestinal exhaust time and the incidence rate of adverse reactions within 48 h after surgery were compared between two groups. Results There were statistical differences in the between-group, time-point and interaction effects of SBP, DBP and HR between two groups (P<0.05), and the fluctuations of the above indicators after anesthesia were smaller in observation group compared with control group (P<0.05). Before anesthesia, the differences in the levels of cortisol and epinephrine between two groups were trivial (P>0.05), but the levels of above-mentioned indicators were significantly lower in observation group than in control group at each time point after anesthesia (P<0.05). The differences between two groups in between-group, time-point and interaction effects of VAS were also statistically significant (P<0.05), and the VAS scores of observation group at different time points after surgery were obviously lower than those of control group (P<0.05). The incidence rate of adverse reactions in observation group was 8.89%, markedly lower than 24.44% in control group (P<0.05). In observation group, the number of patients receiving additional analgesics and postoperative intestinal exhaust time were significantly less or shorter than those in control group (P<0.05). Conclusion Ultrasound-guided quadratus lumborum block combined with propofol anesthesia has a good and stable anesthetic effect in laparoscopic radical resection for colorectal cancer, and it can effectively relieve the pain and reduce the occurrence of postoperative adverse reactions.
Last Update: 2022-05-27