Application of ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第9期
- Page:
- 1128-1132
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application of ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography
- Author(s):
- XIE Mengzhen1; WU Bin1; LIU Yubao1; HOU Yanzhen1; DU Mu1; HE Xiongjun2
- 1. Medical Imaging Center, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China 2. Department of Neurology, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China
- Keywords:
- Keywords: dual-layer spectral detector CT head and neck CT angiography monoenergetic spectral imaging low dose contrast agent
- PACS:
- R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.09.012
- Abstract:
- Abstract: Objective To explore the advantages of dual-layer spectral detector CT using ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography (CTA) for patients with low tolerance to contrast agent. Methods Forty patients with low tolerance to contrast agent were enrolled in observation group. The contrast agent of 20 mL and flow rate of 2 mL/s were used in observation group, and the obtained images were reconstructed by 40 keV monoenergetic spectrum. Meanwhile, 40 general patients in the same period were enrolled in control group. The dosage of contrast agent in control group was 50 mL, and the flow rate was 5 mL/s. The weights of patients in both groups were below 70 kg. The subjective image score, CT value, signal-noise ratio (SNR), contrast to noise ratio (CNR) and radiation dose were compared between two groups. Results There was no statistical difference in the subjective image scores of arterial imaging between two groups (P>0.05). At the level of aortic arch, the CT value, SNR and CNR of observation group were significantly higher than those of control group (P<0.05). In bilateral common carotid artery bifurcation and M1 segment of bilateral middle cerebral artery, no significant difference was found in CT value between two groups (P>0.05), but SNR and CNR of observation group were significantly higher than those of control group (P<0.05). The differences in volume CT dose index, dose length product,and effective radiation dose between observation group and control group were trivial (P>0.05). Conclusion The application of dual-layer spectral detector CT using ultra-low dose and flow-rate contrast injection protocol in head and neck CTA for patients with low tolerance can meet the diagnostic needs, reduce the risk of adverse reactions such as contrast nephropathy and contrast extravasation, and do not increase radiation dose.
Last Update: 2022-09-27