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Application of MRI-CT image fusion technology in delineation of cervical tumor target area(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2022年第5期
Page:
551-555
Research Field:
医学影像物理
Publishing date:

Info

Title:
Application of MRI-CT image fusion technology in delineation of cervical tumor target area
Author(s):
ZHANG Dongyan1 XUE Yanshan2 XU Fang3 SONG Xiaojie1 YAN Baoyun1
1. Department of Imaging, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China 2. Department of Imaging, Second Hospital of Shanxi Medical University, Taiyuan 030000, China 3. Department of Oncology, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China
Keywords:
Keywords: cervical tumor magnetic resonance imaging computed tomography image fusion technology radiotherapy target area
PACS:
R318;R738.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.05.005
Abstract:
Abstract: Objective To explore the effects of MRI-CT image fusion technology on the delineation of cervical tumor target area and dosimetric parameters. Methods The imaging data of 11 patients treated by radiotherapy for cervical tumor were collected. The fusion of MRI and CT images was carried out, and the volume difference and dosimetric difference of the target area delineated based on MRI-CT and CT were compared. The differences in the volume of the target area delineated by different physicians and the dosimetric differences were analyzed. Moreover, intraclass correlation coefficient (ICC) was used for reliability analysis. Results (1) The gross target volume in MRI-CT (GTVMRI-CT) which was delineated by a tumor radiotherapy physician was significantly larger than that of GTVCT, and the volume of spinal cord in MRI-CT (SpineMRI-CT) was significantly smaller than SpineCT (P<0.05). The volume differences of the target area delineated by 5 tumor radiotherapy physicians had the same trends with the results obtained by a tumor radiotherapy physician. The volume overlapping index of the target area delineated based on different images was 0.83±0.15. (2) For the target areas delineated by 5 tumor radiotherapy physicians, the CVMRI-CT of GTV and spine cord was less than CVCT. ICC was 0.97 and 0.95 for GTV, and 0.83 and 0.82 for spinal cord. (3) The MRI-CT Dmax of GTV was significantly lower than CT Dmax, and MRI-CT [D2 cm3] of spinal cord was also significantly lower than CT [D2 cm3] (P<0.05). Conclusion MRI-CT fusion technology is worthy of clinical promotion for it can achieve the accurate target area delineation and radiation dose calculation, not easy to cause missed exposure of the target area. Meanwhile, there are trivial differences among different doctors in using MRI-CT fusion technology, which improves the consistency and reliability of the target area delineation.

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Last Update: 2022-05-27