Abstract

Info

Title:: Evaluating the correlation between pre- and in-treatment target displacements in prostate cancer radiotherapy by multiple acquisition planning CT and cone-beam CT

Author(s):: TIAN Long1; YAN Jiecheng1; LI Minghui2; HU Yimin2; ZHANG Zunhao3; 1. Department of Radiotherapy, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China 2. Department of Radiotherapy, Cancer Institute, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China 3. Department of Radiotherapy, the First Hospital of Hebei Medical University, Shijiazhuang 050000, China

Keywords:: Keywords: prostate cancer multiple acquisition planning CT cone-beam CT implanted marker correlation

Abstract:: Abstract: Objective To evaluate the correlation between the dimensional target displacements before and during treatment for prostate cancer using target displacement data obtained by multiple acquisition planning CT and cone-beam CT, thereby providing some data support for the optimization of treatment planning. Methods Gold implants were implanted in the target areas of 12 prostate cancer patients. Each patient underwent 3 pre-treatment multiple acquisition planning CT scans and 10 in-treatment cone-beam CT scans. The correlation of pre- and in-treatment dimensional target displacements was evaluated by the data obtained in scanning. Results The correlation coefficient R of the displacements in left-right and superior-inferior directions before and during treatment was 0.559 and -0.326, respectively, which indicated moderate and week correlations, without statistical significance. However, the correlation in anterior-posterior direction was relatively strong and statistically significant, with the coefficient R of 0.883. Conclusion Pre-treatment multiple acquisition planning CT can be used to predict the in-treatment target displacements in anterior-posterior direction, thereby optimizing the radiotherapy plan of prostate cancer.