Abstract

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Title:: Pathological and CT manifestations of mesenchymal hamartoma of the liver

Author(s):: YUAN Shijun; LI Jinning; PENG Haiteng; CAI Jing; LIU Huanhuan; ZHANG Caiyuan; WANG Dengbin; Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China

Abstract:: enrolled in the study. All the MHL in 5 children were located at the right lobe of the liver. The MHL in 4 children were double or multilocular cystic, with homogeneous cystic fluid, and the MHL in the other 1 case was cystic-solid, with non-uniform liquid density in the cyst, without enhancement or mild to moderate enhancement in the cystic wallin the cyst. Cystic walls showed no enhancement or mild to moderate enhancement. The 2 MHL lesions in the adult were located at the left and right lobes of the liver respectively, and both of which were solid. The lesions showed a slightly lower density on CT. After enhancement, the majority of the larger lesions had no enhancement, except local slightly and delayed enhancement, and the smaller lesions had slightly and delayed enhancement. Pathologically, the mesenchymal tissues with loose edema were separated into cysts by fibrotic tissues, and hyperplastic bile ducts and blood vessels were observed in pediatric MHL. Microscopically, adult MHL was characterized by hyperplastic and degenerative collagen fibers, with scattered liver cell islands, malformed blood vessels and bile ducts. Conclusion There were commonalities and differences in the clinical, pathological and CT findings of MHL in children and adults, which may be helpful for the clinical diagnosis of MHL.