Application of one-stop multimodal dynamic magnetic resonance imaging in acute stroke and effects of early intervention on ischemic penumbra(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第3期
- Page:
- 307-310
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application of one-stop multimodal dynamic magnetic resonance imaging in acute stroke and effects of early intervention on ischemic penumbra
- Author(s):
- JIANG Yu; CUI Huiqin
- Department of Medical Imaging, The Fourth Affiliated Hospital of Guangxi Medical University (Liuzhou Workers’ Hospital), Liuzhou 545005, China
- Keywords:
- Keywords: acute ischemic stroke; one-stop multimodal plain scanning; ischemic penumbra; magnetic resonance imaging; perfusion-weighted imaging; susceptibility weighted imaging
- PACS:
- R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.03.010
- Abstract:
-
Abstract: Objective To investigate the application of one-stop multimodal dynamic magnetic resonance (MR) imaging in the evaluation of acute stroke and discuss the effects of early intervention on ischemic penumbra. Methods The imaging data of 34 patients with acute stroke were analyzed retrospectively. The parameters such as brain blood flow (CBF) and the mean time-to-peak of contrast agent were compared between normal area and lesion area. Results Diffusion-weighted imaging showed that all patients had different degrees of high signal infarcts, and that 28 patients had different degrees of stenosis and occlusion. In the evaluation of ischemic penumbra, there were 26 cases in which the results obtained by dynamic susceptibility contrast-enhanced MR imaging (DSC) were highly consistent with those obtained by arterial spin-labeling MR imaging (ASL). In the other 8 cases, the results obtained by DSC and ASL were inconsistent, and there was high perfusion in ASL and normal perfusion in DSC, but the ischemic penumbra displayed in DSC was similar to that in ASL, without significant differences (P>0.05). Compared with those in normal area, the levels of central blood volume and CBF in penumbra and infarct areas were lower (P<0.05), and mean transit time in the two areas was longer (P<0.05). Moreover, the levels of CBF and central blood volume in infarct area were lower than those in penumbra area (P<0.05), and the mean transit time in infarct area was longer than that in penumbra area (P<0.05). Conclusion One-stop MR plain scanning can be used to quickly and accurately evaluate acute ischemic stroke, thereby providing objective imaging basis for personalized treatment in clinic.
Last Update: 2020-04-02