Compression elastography and acoustic radiation force imaging in differentiating benign and malignant breast tumors(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第3期
- Page:
- 299-302
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Compression elastography and acoustic radiation force imaging in differentiating benign and malignant breast tumors
- Author(s):
- XU Lei; KANG Ya’ning; MA Jing; YANG Yuanyuan; ZHAO Jun; WANG Rongrong
- Department of Function, Xi’an Hospital of Traditional Chinese Medicine, Xi’an 710021, China
- Keywords:
- Keywords: compression elastography; acoustic radiation force imaging; breast tumor; benign tumor; malignant tumor; differential diagnosis
- PACS:
- R737.9；R445.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.03.008
- Abstract:
- Abstract: Objective To investigate the value of compression elastography (CE) and acoustic radiation force imaging (ARFI) in the differential diagnosis of benign and malignant breast tumors. Methods A total of 71 patients with breast tumors detected by ultrasonography were enrolled, including 89 lesions. The histopathologic examination showed that there were 57 benign lesions and 32 malignant lesions. The lesions were examined by color Doppler ultrasonography, and the elastic strain rate ratio (SR) and virtual touch tissues quantification (VTQ) were calculated by CE and ARFI, separately. The diagnostic efficacy of SR and VTQ in benign and malignant breast tumors was analyzed by receiver operating characteristic (ROC) curve. Results The VTQ and SR in malignant group were significantly higher than those in benign group (P<0.05). The diagnostic efficiency of VTQ and SR in benign and malignant breast tumors was analyzed by ROC curve. The area under VTQ diagnostic curve was 0.918, with a 95% CI of 0.871-0.980 (P<0.05), and the best cut-off value was 3.97. At the best cut-off value, the diagnostic sensitivity and specificity of VTQ were 94.64% and 90.63%, respectively. The area under SR diagnostic curve was 0.899, with a 95% CI of 0.854-0.956 (P<0.05), and the best cut-off value was 4.12. The diagnostic sensitivity and specificity of SR at the best cut-off value were 92.86% and 84.38%, respectively. There was no significant difference in diagnostic sensitivity and specificity between VTQ and SR (P>0.05). Conclusion Both CE and ARFI have high diagnostic value for benign and malignant breast tumors, with similar diagnostic efficacy. The two ultrasound diagnostic techniques can be combined in clinic to achieve complementary advantages and further improve the early detection rate of breast cancer.
Last Update: 2020-04-02