Therapeutic effects of modified Bingpeng powder combined with Yunnan Baiyao on radiation-induced oral mucositis(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第4期
- Page:
- 398-401
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Therapeutic effects of modified Bingpeng powder combined with Yunnan Baiyao on radiation-induced oral mucositis
- Author(s):
- HAN Pengbing1; LI Jin1; JI Xuejuan2; GAO Liying1; ZHANG Guiqiong1
- 1. Department of Radiology, Gansu Provincial Cancer Hospital, Lanzhou 730050, China; 2. Department of Rehabilitation，Xigu District of Lanzhou City Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
- Keywords:
- ; Keywords: radiation-induced oral mucositis; modified Bingpeng powder; Yunnan Baiyao
- PACS:
- R739.6
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.04.006
- Abstract:
- Abstract: Objective To investigate the therapeutic effects of the combined use of modified Bingpeng powder and Yunnan Baiyao on radiation-induced oral mucositis. Methods A total of 82 patients with radiation-induced oral mucositis treated in Gansu Provincial Cancer Hospital from April 2016 to April 2018 were randomly selected and then divided into observation group (41 cases) and control group (41 cases). Two groups of patients received oral pretreatment before radiotherapy, including 3% hydrogen peroxide irrigation, full-mouth ultrasonic teeth cleaning and so on. Control group was given Yunnan Baiyao powder gargle, while observation group was treated with Yunnan Baiyao powder gargle and modified Bingpeng powder. The treatments in both groups began from inflammation to 1 week after the end of radiotherapy. Results The number of patients with oral mucosa of level 0-I in observation group was significantly more than that in control group (P<0.05). Moreover, the number of patients with oropharyngeal pain of grade 0-1 in observation group was significantly more than that in control group (P<0.05). After treatment, the levels of IL-2, IL-4 and TNF-α in the two groups were lower, while the level of IL-10 in the two groups was higher than before. After treatment, the levels of IL-2, IL-4 and TNF-α in observation group were lower than those in control group, and the IL-10 level was higher than that of control group (P<0.05). Conclusion Modified Bingpeng powder combined with Yunnan Baiyao not only has remarkable therapeutic effects on radiation-induced oral mucositis, but also reduce inflammation.
Last Update: 2019-04-23