Abstract

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Title:: Effects of melodic intonation therapy on Broca aphasia recovery and event-related potentials

Author(s):: LI Shun; SONG Chengxian; XUE Senxin; LIN Jun; LIU Xiaolan; Department of Rehabilitation Medicine, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China

Keywords:: ; Keywords: melodic intonation therapy; Broca aphasia; P300; event-related potential

Abstract:: Abstract: Objective To investigate the effects of melodic intonation stimulation on the recovery of auditory comprehension, retelling and audible reading and P300 in patients with Broca aphasia. Methods Forty patients with Broca aphasia were randomly divided into experimental group (n=20) and control group (n=20). In experimental group, some prosodic sentences were used for pronunciation training, and the patients were taught to use exaggerated prosody and stress to express normal language. The patients in control group were treated with conventional speech therapy. Language assessment and examination of (ERP) P300 were performed before treatment and 4 weeks after treatment. Results After treatment, the score of lingual functions in experimental group was significantly improved, with statistical significance (P<0.05). Remarkable improvements were found in auditory comprehension, retelling and audible reading, with statistical significance (P<0.01). Moreover, the abilities to speak and read were also improved, with statistical significance (P<0.05). However, no significant difference was found in the score of calculation, copying, description and dictation (P>0.05). The P300 latency was shortened (P<0.05) and the amplitude was significantly increased (P<0.001). Conclusion The patients with Broca aphasia can benefit from melodic intonation therapy, and P300 can be used as an objective index to evaluate the recovery of Broca aphasia.