Abstract

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Title:: Relationship between the MRI measurements of apparent diffusion coefficient and signal intensity ratio and the development of osteoporostic lumbar vertebrae

Author(s):: PENG Haizhou1; ZHANG Zijun1; ZHAO Wen1; ZHENG Xiaofeng2; 1. Department of Orthopedics, Beijing Aerospace Hospital, Beijing 100076, China; 2. Department of Radiology, Beijing Aerospace Hospital, Beijing 100076, China

Keywords:: ; Keywords: lumbar vertebrae; magnetic resonance imaging; apparent diffusion coefficient; signal intensity ratio; osteoporosis

Abstract:: Abstract: Objective To investigate the correlation between the apparent diffusion coefficient (ADC) and signal intensity ratio (SIR) measured by magnetic resonance imaging (MRI) and the occurrence and development of osteoporotic lumbar vertebrae. Methods A total of 235 patients receiving bone mineral density (BMD) scans from March 2011 to January 2017 were enrolled, and then divided into osteopenia group (n=52), osteoporosis group (n=85) and normal group (n=98) according to the results of dual-energy X-ray absorptiometry. The ADC and SIR of the L2-4 vertebral body of all subjects were measured by MRI, and the correlation between the MRI measurements of ADC and SIR and the BMD measured by dual-energy X-ray absorptiometry were analyzed. Results Compared with those of osteopenia group and normal group, the ADC of osteoporosis group was significantly decreased, while the SIR was significantly increased, with statistical significance (P<0.05). ADC was positively correlated with BMD (r=0.325, P=0.006), and SIR was negatively correlated with BMD (r=-0.601, P=0.001). Conclusion The ADC and SIR measured by MRI have good correlations with BMD. Both ADC and SIR can be used to quantitatively evaluate osteoporotic vertebral body and reflect the occurrence and development of osteoporotic lumbar vertebrae.