Effects of oral diatrizoate on the dose distribution of volumetric modulated arc therapy for cervical cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第5期
- Page:
- 525-528
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Effects of oral diatrizoate on the dose distribution of volumetric modulated arc therapy for cervical cancer
- Author(s):
- WU Xiaowei1; 2; CUI Xiangli1; 2
- 1. Anhui Provincial Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institute of Physical Sciences, Chinese Academy of Sciences, Hefei 230031, China; 2. Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Sciences, Hefei 230031, China
- Keywords:
- ; Keywords: cervical cancer; volumetric modulated arc therapy; oral diatrizoate; dose distribution
- PACS:
- R730.55
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.05.006
- Abstract:
- Abstract: Objective To discuss the effects of oral diatrizoate on the dose distribution of volumetric modulated arc therapy (VMAT) for cervical cancer. Methods The CT images of 12 cervical cancer patients after taking oral diatrizoate were selected and VMAT (Plan A) was designed for each patient. Based on the same CT images, the CT value of contrast area in intestine was changed to the value of intestinal content, and the other parameters remained unchanged. The VMAT plan was transplanted on the CT image with the CT value of intestinal content (Plan B), and the dose distribution was re-calculated. The dosimetric differences were analyzed by assessing the deviation of dose distribution of target areas and organs-at-risk between Plan A and Plan B. Results Both Plan A and Plan B had similar conformity index and homogeneity index of target areas (P>0.05). The relative percentages of minimum dose, maximum dose and mean dose between Plan A and Plan B was 0.07, 0.15 and 0.09, respectively (P=0.32, 0.59, 0.00). For the dosimetirc parameters of organs-at-risk, statistical differences were only found in intestine, and the relative percentage of the V40, V30 and V20 of intestine were 0.11, 0.16 and 0.03, respectively (P=0.03, 0.03, 0.03). Conclusion The effect of oral diatrizoate on dose distribution was statistically significant for both the mean dose of planning target areas and the dose distribution of intestine. However, the clinical analysis reveals that the absolute differences of dose distribution caused by oral diatrizoate can be neglected.
Last Update: 2019-05-23