Effects of different uncertainty settings in Monaco treatment planning system on computation efficiency and dosimetric accuracy(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第7期
- Page:
- 766-770
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Effects of different uncertainty settings in Monaco treatment planning system on computation efficiency and dosimetric accuracy
- Author(s):
- LI Chenguang1; ZHAO Jingjing2; LI Zhengxian3; LI Tian2; NIU Xiaoyu1; YUE Haizhen2
- 1. Department of Marine Technology, Ocean University of China, Qingdao 266100, China; 2. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China; 3. Department of Radiotherapy, Jilin Guowen Hospital, Gongzhuling 136100, China
- Keywords:
- ; Monaco treatment planning system; uncertainty; computation efficiency; dosimetric accuracy
- PACS:
- R144.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.07.005
- Abstract:
- Abstract: Objective To compare the accuracy and efficiency of dose calculation using two uncertainty settings in Monaco treatment planning system, namely Per Calculation (PC) and Per Control Point (PCP). Methods Thirty intensity-modulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT) plans, including 15 for thoracic cancer and 15 for nasopharyngeal carcinoma, were included in this study. According to the decreasing accuracy of dose calculation, 5 groups of PC and 6 groups of PCP, with a total of 11 parameters, were selected in this study. The effects of uncertainty settings on computation time and dosimetric evaluation indicators were evaluated. Results The computation time (s) was 131.780±26.910, 6.76±3.57, 1.75±0.57, 0.84±0.24 and 0.84±0.24 for PC, and 259.20±80.15, 73.53±26.00, 9.18±3.26, 3.60±1.67, 1.59±0.75 and 1.13±0.49 for PCP, respectively. The computation time of PC and PCP was negatively correlated with the accuracy of dose calculation, with statistical significance (P<0.05). The box plot analysis of dosimetric evaluation indicators between two settings showed smaller interquartile ranges among the mean dose and several dose-volume indexes, and larger interquartile ranges in the maximum dose and global maximum dose. Single factor ANOVA analysis of different dosimetric evaluation indicators showed no statistical differences between two uncertainty settings (P<0.05). Conclusion The two uncertainty settings can be used in the clinical treatment planning. The global maximum dose is positively correlated with uncertainty, while the computation time is negatively correlated with uncertainty. PC/PCP settings have marginal effects on the mean dose and specific dose-volume indexes, but significant effects on the global maximum dose and the maximum dose to the serial organs.
Last Update: 2018-07-24