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 Testing research on a realistic pediatric abdominal phantom with CT enhancement constructed with 3D printing technology(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2019年第3期
Page:
307-310
Research Field:
医学影像物理
Publishing date:

Info

Title:
 Testing research on a realistic pediatric abdominal phantom with CT enhancement constructed with 3D printing technology
Author(s):
 OUYANG Rongzhen1 SUN Aimin1 WANG Qian1 GUO Chen1 LI Jianying2 HU Liwei1 ZHONG Yumin1
 1. Department of Radiology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China; 2. CT Research Center of GE, Shanghai 201203, China
Keywords:
 Keywords: 3D printing technology computed tomography abdominal phantom pediatric
PACS:
R318
DOI:
DOI:10.3969/j.issn.1005-202X.2019.03.012
Abstract:
 Abstract: Objective To construct a realistic pediatric abdominal phantom with CT enhancement, and validate its X-ray attenuation properties by comparing phantom images with the enhanced abdominal CT images of normal children. Methods Based on the rapid prototyping of 3D printing technology, polyurethane and tris (2-chloroethy) phosphate (TCEP) were used as printing materials. The TCEP mixed materials of different concentrations (0%-60%) was used to investigate the linear relationships between the concentration of TCEP mixed materials and CT values at different tube voltages (80-120 kV). According to the CT imaging data of the patient, a pediatric abdominal phantom with CT enhancement in the arterial phase was designed and printed. The printed phantom was scanned with CT for 3 times to assess the reproducibility. And then the phantom CT images were compared with the CT images of normal children. The CT values, image noises and contrast-to-noise ratios of liver, abdominal aorta, kidney cortex, spleen and muscle were measured. Finally, the subjective image quality was assessed by two radiologists using a 5-point scale. Results A good linear relationship was found between CT value and TCEP concentration at all tube voltages (P<0.001, r=0.99). The CT values of all tissues were similar between phantom and normal children (all P>0.05), except for the CT value of abdominal aorta. The contrast-to-noise ratios of liver, kidney cortex and spleen in phantom images were higher than those in the images of normal children (7.08±0.83 vs 5.50±0.48, 14.18±2.48 vs 10.67±1.05, and 11.84±1.69 vs 8.78±0.53, respectively). The phantom images and CT images of normal children had similar image noise [(12.3±1.47) HU vs (13.7±1.5) HU]. However, the subjective image quality scores of phantom images were slightly lower (4.35±0.17 vs 4.72±0.17, 4.50±0.16 vs 4.65±0.12). Conclusion Using the rapid prototyping of 3D printing technology to construct realistic phantom is proved to be feasible. The phantom image has a high quality and consistent attenuation characteristics. The realistic pediatric phantom can be used to simulate the attenuation characteristics of patients of different body shapes, so as to optimize dose distribution and reconstruction algorithms.

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Last Update: 2019-03-25