Abstract

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Title:: Different-field intensity-modulated radiotherapy vs four-field three-dimensional conformal radiotherapy following radical surgery for cervical carcinoma: a dosimetry comparison

Author(s):: TANG Shiqiang1; 2; QIU Xiaoping1; CHEN Wentao2; HE Kui2; WANG Zhifang2; HE Zhipeng2; 1. School of Nuclear Science and Technology, University of South China, Hengyang 421001, China; 2. Radiation Therapy Center, Chenzhou NO.1 People’s Hospital, Chenzhou 423000, China

Keywords:: ; cervical carcinoma; different fields; intensity-modulated radiotherapy; three-dimensional conformal radiotherapy; dosimetry

Abstract:: Objective To compare the dosimetry of different-field intensity-modulated radiotherapy (IMRT) with four-field three-dimensional conformal radiotherapy (3DCRT) after radical surgery for cervical carcinoma for evaluating the dose distributions, and select the optimal treatment plan according to different situations. Methods Twenty patients receiving radical surgery for cervical carcinoma were selected, and different plans, namely three-, five- and seven-field IMRT plan and four-field 3DCRT, were designed for each patients. Based on the dose-volume histogram (DVH), the irradiation dose of target areas, normal tissues and organs, the conformal index and homogeneity index of dose distributions in target areas were compared. Results The conformal index and dose coverage of target areas in three-, five-and seven-field IMRT was superior to those in four-field 3DCRT, while the differences in homogeneity index were trivial. The irradiation doses of bladder, rectum, small intestine in IMRT were statistically lower as comparison with four-field 3DCRT. Conclusion IMRT should be more widely used in clinic for it can ensure the irradiation dose of tumor and reduce the incidence of complication. Moreover, compared with four-field 3DCRT, three-field IMRT is more beneficial for patients with poor economic conditions