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Title:: CyberKnife technology and its application in the treatment of prostate cancer

Author(s):: LI Yanyan1; 2; CHEN Tianmei1; 2; HE Jie1; 2; ZENG Fubin1; 2; ZHANG Huojun2; 1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China 2. Department of Radiation Oncology, Changhai Hospital Affiliated to Naval Medical University, Shanghai 200433, China

Keywords:: Keywords: CyberKnife prostate cancer stereotactic body radiotherapy dosimetry clinical application review

Abstract:: Abstract: Prostate cancer is one of the most common malignant tumors among males worldwide, and its treatment objective is to effectively control the tumor while maximally preserving patients quality of life. With the rapid advancement of medical imaging and radiotherapy technologies, stereotactic body radiotherapy and radiosurgery have become important modalities in prostate cancer management. As an advanced frameless, image-guided radiotherapy system, CyberKnife demonstrates significant advantages in the precise treatment of prostate cancer, owing to its unique capabilities in real-time image tracking, automatic compensation, and highly conformal dose shaping. This review summarizes the current applications of CyberKnife technology in prostate cancer treatment, focusing on its dosimetric advantages, clinical efficacy, treatment-related toxicities, and comparisons with other treatment modalities. In addition, future development prospects are discussed.