Diagnostic value of MRI plain scan combined with contrast-enhanced scan in cervical cancer staging(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2025年第8期
- Page:
- 1052-1056
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic value of MRI plain scan combined with contrast-enhanced scan in cervical cancer staging
- Author(s):
- LI Daoming1; YANG Ling2
- 1. Department of Radiology, Mianyang 404 Hospital (the First Peoples Hospital of Mianyang), Mianyang 621000, China 2. Department of Gynecology, Jiepai Community Health Service Center of Anzhou District, Mianyang 621000, China
- Keywords:
- Keywords: cervical cancer tumor staging magnetic resonance imaging plain scan contrast-enhanced scan
- PACS:
- R816.91；R737.33
- DOI:
- DOI:10.3969/j.issn.1005-202X.2025.08.011
- Abstract:
- Abstract: Objective To analyze the value of magnetic resonance imaging (MRI) plain scan and contrast-enhanced scan in the staging of cervical cancer. Methods A cohort of 82 cervical cancer patients were enrolled and stratified into 3 pathological stages (I, II, and III-IV). Concurrently, 30 healthy volunteers served as controls. All participants underwent MRI plain scan and dynamic contrast-enhanced MRI (DCE-MRI). Through the comparative analysis of DCE-MRI parameters between healthy controls and cervical cancer patients, and stratified evaluation across stages I, II, and III-IV, the relationships of DCE-MRI parameters with tumor type, differentiation grade, and lymph node metastasis in cervical cancer patients were explored, and the diagnostic performances of MRI plain scan and DCE-MRI in cervical cancer staging were compared. Results The volume transfer constant (Ktrans), rate constant (Kep), and extracellular extravascular volume fraction (Ve) demonstrated significant elevations in cervical cancer patients compared to healthy controls (P<0.05). Stage III-IV patients exhibited the highest Ktrans, Kep, and Ve, followed by stage Ⅱ patients and stage Ⅰ patients. All inter-stage comparisons reached statistical significance (P<0.05). The Ktrans and Ve in patients with adenocarcinoma were higher than those in patients with squamous cell carcinoma the poorly differentiated exhibited the highest Ktrans, Kep, and Ve, followed by the moderately differentiated and the high differentiated and those with lymph node metastasis demonstrated significantly elevated Ktrans and Kep than those without lymph node metastasis (P<0.05). The areas under the curve (AUC) of MRI plain scan, Ktrans, Kep, and Ve for diagnosing stage III-IV cervical cancer were 0.678, 0.775, 0.731, and 0.695, respectively. The MRI plain scan combined with DCE-MRI demonstrated superior diagnostic performance (AUC=0.859) over individual parameters, with a sensitivity of 90.91% and a specificity of 67.61%. Conclusion The combination of MRI plain scan and DCE-MRI is of high value in cervical cancer staging.
Last Update: 2025-09-15