Abstract

Info

Author(s):: CHEN Minghui1; WU Tong1; SHAO Yi2; LI Fugang3; CHEN Liuxiao1; ZHOU Jing1; WANG Hongwang1; SONG Chengli1; 1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2. Departmentof Urology, Shanghai First People’s Hospital, Shanghai 200080, China; 3. Shanghai Aopu Biopharmaceutical Co., Ltd., Shanghai201201, China

Keywords:: low temperature plasma ablation; bipolar pulse; thermal injury; ablation device

Abstract:: Although low temperature plasma ablation technology has significant advantages in clinical applications, its poorstability, high power consumption and thermal injuries to the tissues are still key factors limiting its widespread use. Toaddress these issues, a device that uses bipolar pulses to excite plasma is developed, and it can flexibly adjust its outputvoltage, frequency and duty cycle, effectively reducing breakdown voltage and power consumption. By conductingsimulation and saltwater discharge experiments, the excitation process of plasma is elaborated in detail. Meanwhile, theeffects of two different pulse excitation modes on plasma excitation are discussed and compared. The results show that thebipolar pulse excitation mode is advantageous in reducing discharge current and breakdown voltage, and shortening theformation time of the vapor layer, which effectively relieves thermal injuries to the tissues. Finally, the broad applicationpotential of the plasma ablation device is demonstrated in plasma ablation experiments which are conducted at differentvoltages, with pork as the experimental material. The study provides a new theoretical basis and practical guidance for theapplication of plasma ablation technology in minimally invasive surgery.