Dosimetric comparison of tomotherapy, static IMRT and VMAT techniques in radiotherapy forcervical cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2025年第4期
- Page:
- 429-434
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric comparison of tomotherapy, static IMRT and VMAT techniques in radiotherapy forcervical cancer
- Author(s):
- GOU Liangqian; WU Shuyu; LIAO Huaying; YANG Yushan; ZHANG Guoqian; YU Hui; WANG Xiaohui; ZHANG Shuxu
- Radiotherapy Center, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, China
- Keywords:
- cervical cancer; tomotherapy; volumetric modulated arc therapy; static intensity-modulated radiotherapy;
dosimetry
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- PACS:
- R737.33；R811.1
- DOI:
- 10.3969/j.issn.1005-202X.2025.04.002
- Abstract:
- Objective To compare the dosimetric disparities among static intensity-modulated radiotherapy (IMRT),volumetric modulated arc therapy (VMAT), and tomotherapy (TOMO) techniques in cervical cancer radiotherapy forproviding data support for clinical decision-making scheme of radiotherapy. Methods The clinical data of 19 cervical cancerpatients, treated at the Affiliated Cancer Hospital and Institute of Guangzhou Medical University from February to May in2024, were analyzed. Three plans were devised for each case using IMRT, VMAT, and TOMO techniques, followed bydosimetric evaluation in terms of various metrics such as dose volume parameters of the target areas as well as organs-at-risk(OAR), conformity index (CI), homogeneity index (HI), and delivery time. Results All 3 plans met the clinical prescriptionrequirements for the target areas. Compared with static IMRT and VMAT, TOMO had significantly lower Dmean and DmaxofPCTV and PGTVnd. For OAR, TOMO demonstrated significant advantages over IMRT and VMAT in the Dmean of thebladder, the Dmean, Dmax, V30, V40of the rectum, the Dmean, Dmax, V20, V30of left and right femoral heads, and the Dmean, V20, V50ofthe pelvis (P<0.05). In addition, the TOMO group showed significantly higher CI for both PCTV and PGTVnd as comparedwith IMRT and VMAT groups, and lower PGTVnd HI than IMRT group (all P<0.05). Although there was trivial differenceamong 3 groups in term of PCTV HI, TOMO group performed slightly better than the other two groups. Notably, VMATtechnique had the shortest treatment time. Conclusion In various treatment modalities for cervical cancer, TOMO is superior to IMRT and VMAT in terms of target dose coverage, OAR dose distribution, CI, and HI. However, VMAT has the highestefficiency.
Last Update: 2025-04-30