Superconducting magnetocardiography signal measurement technology and coronary heart disease screening(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2024年第10期
- Page:
- 1265-1272
- Research Field:
- 医学信号处理与医学仪器
- Publishing date:
Info
- Title:
- Superconducting magnetocardiography signal measurement technology and coronary heart disease screening
- Author(s):
- AI Haiming1; DONG Zhe2; GE Jingru3; MI Wang4; LIU Wei5
- 1. College of Science and Technology, Beijing Open University, Beijing 100081, China 2. Department of Cardiology, China-Japan Friendship Hospital, Beijing 100029, China 3. Beijing Institute of Petrochemical Technology, Beijing 102617, China 4. Beijing Milestone Science & Technology Development Co., Ltd., Beijing 100086, China 5. Department of Cardiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing 100035, China
- Keywords:
- Keywords: magnetocardiography signal superconducting quantum interference device inverse solution electrocardiography signal coronary heart disease
- PACS:
- R318
- DOI:
- DOI:10.3969/j.issn.1005-202X.2024.10.011
- Abstract:
- Abstract: Objective To research superconducting magnetocardiography signal measurement technology and coronary heart disease screening for solving the difficulties in weak magnetocardiography signal measurement, and to verify the value of clinical application. Methods The principle of superconducting magnetocardiography signal measurement technology was analyzed for constructing a framework for superconducting magnetocardiography signal measurement technology. Then, the key circuits such as the host controller, magnetic flux-locked loop, and signal conditioning module were designed, and software systems and core algorithms were developed. Finally, a total of 255 volunteers with healthy hearts, mild myocardial ischemia and severe myocardial ischemia were enrolled in the study, and a comparative experiment was performed between synchronous magnetocardiography and coronary angiography (CAG). Results The peer-to-peer bipolar structure was only observed in the current density vector distribution of healthy subjects instead of myocardial ischemia subjects. The overall coincidence rate, total Kappa value, severe ischemia coincidence rate, mild ischemia coincidence rate and negative coincidence rate of magnetocardiography with CAG were 86.22%, 78.21%, 86.79%, 84.09% and 86.67%, respectively. Magnetocardiography had a sensitivity, specificity, positive rate, negative rate, positive likelihood ratio and negative likelihood ratio of 87.16%, 84.41%, 86.00%, 86.67%, 5.98 and 0.08, respectively. Conclusion Magnetocardiography has a high coincidence rate and consistency with CAG in the diagnosis of myocardial ischemia. Superconducting magnetocardiography signal measurement technology can be served as an accurate and reliable screening method for coronary heart diseases.
Last Update: 2024-10-29