Numerical simulation of hemodynamics in internal carotid artery stenosis(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2024年第10期
- Page:
- 1273-1280
- Research Field:
- 生物材料与力学
- Publishing date:
Info
- Title:
- Numerical simulation of hemodynamics in internal carotid artery stenosis
- Author(s):
- PENG Hongmei1; ZHANG Dongwei2; ZUO Tao1; LIU Baozhi2; CHEN Yang1
- 1. College of Physics and Electronic Information, Inner Mongolia Minzu University, Tongliao 028000, China 2. Department of Neurology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028007, China
- Keywords:
- Keywords: internal carotid artery stenosis?hree-dimensional vascular reconstruction?umerical simulation two-phase blood flow computational fluid dynamics
- PACS:
- R318；O357；O241
- DOI:
- DOI:10.3969/j.issn.1005-202X.2024.10.012
- Abstract:
- Abstract: Objective To investigate the hemodynamic characteristics of carotid artery models with different degrees of artificial arterial stenosis based on hemodynamic numerical simulation, and to analyze causes of internal carotid artery stenosis and the diseases due to the stenosis from the perspective of hemodynamics. Methods Two-dimensional CT data of healthy individuals were collected from Affiliated Hospital of Inner Mongolia Minzu University, and the three-dimensional model of carotid artery was reconstructed from the two-dimensional CT data using medical modeling software MIMICS20.0. Subsequently, the obtained carotid artery model was imported to 3-Matic Medical software and interfered with various degrees of artificial internal carotid artery stenosis at the same location to obtain the models with 25%, 50% and 75% internal carotid artery stenosis. After format conversion, boundary condition setting and mesh generation, the models were imported to computational fluid dynamics software FLUENT14.5 for the hemodynamic numerical simulation and analysis of the carotid artery and two-phase blood flow. Results The comparison of the blood streamlines and velocity vector maps of 3 different degrees of internal carotid artery stenosis at the same location revealed that with the increase of stenosis severity, the phenomenon of blood vortex flow at the carotid sinus decreases rapidly, but obvious vortex flow appeared above and below the internal carotid artery stenosis, and the blood flow was selectively deflected. During the internal carotid artery stenosis from 25% to 50% and then to 75%, the pressure on the wall of internal carotid artery was always low, and the pressure on the wall of internal carotid artery was gradually increased, forming a high pressure area. There was high shear stress area at the stenosis, and the low shear stress ranges above and below the stenosis were obviously larger. Conclusion The technology of using computer software to obtain models with artificial stenosis is convenient and efficient. When the internal carotid artery stenosis increases from 25% to 50% and then to 75%, the blood flow of the carotid artery changes obviously, obvious vortex flow appears in the internal carotid artery, and the mechanical properties of the wall of the carotid artery also change.
Last Update: 2024-10-29