Repeatability study on quantization parameters of intravoxel incoherent motion obtained by different estimation methods(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第10期
- Page:
- 1251-1254
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Repeatability study on quantization parameters of intravoxel incoherent motion obtained by different estimation methods
- Author(s):
- ZHANG Zixiong1; YANG Manman1; ZHANG Jingjing1; QIAO Wenjun1; XIONG Xiaoli2
- 1.Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China 2. Department of Radiology, Hainan Affiliated Hospital of Hainan Medical University, Haikou 570311, China
- Keywords:
- Keywords: renal cortex diffusion weighted imaging incoherent motion double exponential model
- PACS:
- 1005-202X（2023）10-1251-04
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.10.011
- Abstract:
- Abstract: Objective To study the repeatability of intravoxel incoherent motion (IVIM) parameters of diffusion weighted imaging (DWI) in normal renal cortex obtained by two different estimation methods. Methods Eighteen volunteers were enrolled and underwent free-breathing abdominal-renal multi-b-value DWI twice using Philips Ingenia 3.0T magnetic resonance imaging equipment. Based on the double exponential model, the quantization parameter maps (D, D*, f) of IVIM were calculated from multi-b-value DWI data using non-linear least squares (NLLS) method and Bayesian estimation (Bayes) method. Three equally sized regions of interest were selected from bilateral renal cortex, and the mean of each parameter was calculated. Th repeatability of each parameter estimated by the two methods was analyzed using Bland-Altman method. Results The coefficients of variation of parameters D, f, and D* calculated by Bayes method between two scans were 37.4%, 30.0%, and 64.0%, respectively while those calculated by NLLS method between two scans were 40.7%, 35.2%, and 53.7%, respectively. The coefficients of variation of parameters D and f calculated by Bayes method were lower than those of NLLS method, indicating that Bayes method had better consistency and the coefficient of variation of D* obtained by NLLS method was lower than that of Bayes method, indicating that NLLS method had better consistency. Conclusion The stability and reliability of various quantitative parameters in the renal cortex can be improved by two methods based on double exponential model：using Bayes method to obtain parameters D and f, and using NLLS method to obtain parameter D*.
Last Update: 2023-10-27