Abstract

Info

Title:: Predicting the formation of aortic dissection using a non-Newtonian model

Author(s):: WANG Miao1; YAO Ji1; SUN Yi2; WANG Huimin1; ZHANG Hongming1; 1. School of Architectural Engineering, Kunming University of Science and Technology, Kunming 650500, China 2. Department of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China

Keywords:: Keywords: aortic dissection bidirectional fluid-solid coupling non-Newtonian blood hemodynamics hypertension

Abstract:: Abstract: The blood flow in the aortic arch and branch vessels in vitro is simulated, and the blood model is optimized with a non-Newtonian model. A numerical simulation analysis is conducted based on bidirectional fluid-solid coupling to analyze the hemodynamic characteristics (blood flow velocity, vascular wall pressure and vascular wall stress) in a cardiac cycle, and discuss their relationships with the formation of aortic dissection. It is concluded that the long-term existence of "chaotic" blood flow distribution in the blood vessel and the sudden changes of wall pressure and wall stress are liable to cause changes in the structure and function of the cells of the arterial wall, and ultimately induce the formation of aortic dissection. The study provides a more reliable basis for medical diagnosis, and further protects the life, health and safety of patients.