Abstract

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Title:: Diagnostic value of CT cavity features in drug-resistant pulmonary tuberculosis

Author(s):: ZHENG Qiuting1; GUO Lin2; XIA Li2; LUO Weijun1; ZHONG Cheng1; DENG Yingying3; XU Chuanjun4; LURE Y.M. Fleming1; 2; LU Puxuan1; 1. Department of Medical Imaging, Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China 2. Shenzhen Zhiying Medical Imaging Co., Ltd., Shenzhen 518109, China 3. Department of Imaging, Yantian District Peoples Hospital, Shenzhen 518081, China 4. Department of Imaging, Nanjing Second Peoples Hospital, Nanjing 210000, China

Keywords:: Keywords: pulmonary tuberculosis cavity differential diagnosis computed tomography

Abstract:: Abstract: The diagnostic value of cavity features in CT for drug-resistant pulmonary tuberculosis (DR-PTB) and drug-sensitive pulmonary tuberculosis (DS-PTB) is analyzed for improving the CT diagnosis and differential diagnosis of DR-PTB. A retrospective study is conducted on 323 DR-PTB patients and 160 DS-PTB. DR-PTB and DS-PTB groups are compared in terms of the incidence of cavities, lung involvement, the number of cavities, the appearance of cavities in nodules (masses) or consolidation, the size and roundness of the outer and inner diameters of cavities, and the thickness of cavity walls. Compared with DS-PTB group, DR-PTB group has higher incidence of cavities, more cavities. The ratio of multiple cavities and 3 or more lung lobes involved and the ratio of cavities in pulmonary nodules (mass) in DR-PTB patients are significantly higher than those in DS-PTB group. Cavities are more widely distributed in DR-PTB patients. There are significant differences in CT cavity features, including the external diameter, internal diameter, and mean cavity wall thickness for DS-PTB and different types of DR-PTB, as well as within groups of different types of DR-PTB (P<0.05). CT features based on cavitation have significant values in distinguishing DR-PTB and DS-PTB.