Clinical study of different bronchoscopic lavage timings in the treatment of adenovirus pneumonia in children(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第12期
- Page:
- 1569-1573
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Clinical study of different bronchoscopic lavage timings in the treatment of adenovirus pneumonia in children
- Author(s):
- XIE Bing1; LIU Chunhua2
- 1. Childrens Respiratory Area 1, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. Department of Pediatrics, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China
- Keywords:
- Keywords: bronchoscopic lavage children adenovirus pneumonia disease course
- PACS:
- R725.6
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.12.018
- Abstract:
- Abstract: Objective To explore the effect of the timing on the efficacy of bronchoalveolar lavage in children with adenovirus pneumonia. Methods According to the timing of bronchoscopic lavage, 62 children receiving bronchoscopic lavage for adenovirus pneumonia were divided into early group (n=31, received bronchoscopic lavage within <10 d of the disease course) and late group (n=31, received bronchoscopic lavage within ≥10 d of the disease course). The therapeutic effect and the clinical related indexes after lavage were evaluated. Before and after 48 h of lavage, blood gas indexes ［fluorescein/protein binding ratio (F/P), partial pressure of arterial carbon dioxide (PaCO2), partial pressure of oxygen in arterial blood (PaO2), blood oxygen saturation (SpO2)］, physical indexes ［heart rate (HR), respiratory rate (RR), mean arterial pressure (MAP)］ and infection analysis indicators ［C-reactive protein (CRP), white blood cell count (WBC)］ were evaluated and compared. The occurrences of complications in both groups were also recorded. Results The total response rate in early group was higher than that in late group (96.77% vs 80.65%, P<0.05). The number of cases undergoing mechanical ventilation after lavage in early group was less than that in late group, and the duration of fever, disappearance time of lung rale and hospital stay were shorter in early group (P<0.05). After lavage, early group had higher PaO2, F/P and SpO2, and lower PaCO2, CRP and WBC as compared with late group (P<0.05). There was no significant difference in physical signs between the two groups before and after lavage (P>0.05). Conclusion Receiving bronchoscopic lavage within <10 d of the disease course can improve treatment outcome of adenovirus pneumonia in children.
Last Update: 2022-12-23