《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第2期
- Page:
- 157-162
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- -
- Author(s):
- WANG Jiaqi1; 2; CUI Yong2; LUAN Kun2; LI Chenguang3; ZHANG Yibao3
- Keywords:
- dual-phase 18F-FDG PET/CT brain tumor maximum standardized uptake value semiquantitative analysis
- PACS:
- R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.02.005
- Abstract:
- Objective To investigate the value of dual-phase PET/CT in the initial diagnosis and follow-up of brain tumor. Methods A retrospective analysis was conducted on the initial diagnosis and follow-up cases (n=31) of brain tumors using dual-phase 18F-FDG PET/CT. Based on the qualitative analysis by pathological or imaging examination, the SUVmax value of the lesion in the dual-phase scans was semi-quantitatively analyzed, and the specific critical value of dual-phase FDG PET/CT scan was determined according to ROC analysis to distinguish the tumor activity. Results The sensitivity, specificity and accuracy of delayed scan were 88.9%, 100.0% and 97.9%, higher than 80.6%, 99.9% and 96.3% of routine scan (P<0.001), indicating that delayed scan can further clarify the nature of the lesion. In patients with viable lesions, the SUVmax of contralateral caudate nucleus head (CCH) of delayed scan differed from that of routine scan (P<0.001). The semi-quantitative analysis showed that there were statistical significance between delayed scan and routine scan in target ratios of contralateral white matter (CWM), ipsilateral cerebellar cortex (ICC) to viable lesion (Target, T), and the intergroup comparison between viable lesion and the overall (viable and nonviable lesions) (P<0.001). According to the accuracy, sensitivity and specificity obtained by ROC analysis on the percentage change, ICC had the optimal diagnostic efficiency, followed by CWM and CCH. The sensitivity, specificity, accuracy were 77.8%,72.7%, 90.1% for ΔT/CWM, 88.9%, 54.5%, 91.1% for ΔT/CCH, and 83.3%, 72.7%, 93.4% for ΔT/ICC. Conclusion Dual-phase PET/CT examination has certain feasibility and clinical application value for improving the accuracy of brain tumor activity diagnosis.
Last Update: 2023-03-03