Abstract

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Title:: Effects of aortic outlet blood pressure on left ventricular blood flow characteristics

Author(s):: LI Rennian1; LI Zhixiong1; HAN Wei1; FENG Huimin1; HAO Yingjian1; REN Jiale1; QIANG Yan1; 2; 1. School of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China 2. School of Energy and Environment, Southeast University, Nanjing 210096, China

Keywords:: Keywords: heart left ventricle blood pressure dynamic grid blood flow characteristic

Abstract:: Abstract: Mimics is used for the 3D reconstruction of the heart, and 3-matic for model optimization and model error analysis. A velocity distribution assumption is made for the left ventricular wall motion, and the left ventricular wall motion is programmed based on the UDF macro file. The blood is regarded as a non-Newtonian fluid, and the effects of different blood pressures on left ventricular blood flow characteristics are analyzed with dynamic grid technique. The simulation results show that when the left ventricle contracts, there are obvious pressure gradient and decreasing internal pressure and that when the left ventricle relaxes, the internal pressure gradually increases. The velocity at the mitral valve orifice increases first and then decreases. With the elevation of blood pressure, the shear stress in the left ventricle continues to increase, which can easily destroy the structure of red blood cells, causing hemolysis and leading to cardiac dysfunctions.