Comparison among 3 different SRS techniques in the treatment of single or multiple brain metastases(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第11期
- Page:
- 1329-1333
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Comparison among 3 different SRS techniques in the treatment of single or multiple brain metastases
- Author(s):
- WEI Xiaping1; SU Jiehong1; LIN Chujie1; ZHU Yi1; LIU Yeming1; HUANG Mingchao1; HUANG Xiaowei2; SHI Junyue3
- 1. Department of Radiation Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510168, China 2.Office for Science and Technology, Dongguan University of Technology, Dongguan 523808, China3. Department of Radiation Oncology, Foresea Life Insurance Guangzhou General Hospital, Guangzhou 511300, China
- Keywords:
- Keywords: brain metastasis volumetric modulated arc therapy dosimetric comparison HyperArc CyberKnife
- PACS:
- R739.41；R815.6
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.11.002
- Abstract:
- Abstract: Objective To compare the dosimetric differences among HyperArc (HA), volumetric modulated arc therapy (VMAT) and CyberKnife (CK) in the radiotherapy of single or multiple brain metastases. Methods The CT images of 75 cases of brain metastases were divided into 5 groups (1 BM, 4 BM, 8 BM, 15 BM, 20 BM), and 3 different treatment plans (HA, nCO-VMAT and CK) were designed for each case. The treatment plans were evaluated and compared in terms of conformity index (CI), gradient index (GI), mean dose to normal brain tissues (Brainmean), total monitor units (MU) and delivery time. Results In the cases of 1 BM and 4 BM, GI (1 BM: P=0.429 4 BM: P=0.334) and [Brainmean ](1 BM: P=0.799 4 BM: P=0.317) did not differ significantly among HA, nCO-VMAT and CK and the CI of HA was close to that of nCO-VMAT, and both of them were higher than that of CK (1 BM: P<0.001 4 BM: P<0.001). In the cases of 8 BM, the CI of HA and nCO-VMAT was close and higher than that of CK (P<0.001), and the GI of HA and CK were close and higher than that of nCO-VMAT (P<0.001). In the cases of 15 BM, HA had the optimal CI among 3 different plans and CK had the lowest GI (P<0.001) and [Brainmean ] (P<0.001), followed by HA and nCO-VMAT. In the cases of 20 BM, the optimal CI was found in HA (P<0.001) CK has the minimum GI (P<0.001), followed by HA and nCO-VMAT. In all groups, MU of both HA and nCO-VMAT were lower than that of CK, and the beam delivery time of CK was much longer than those of HA and nCO-VMAT. Conclusion All these techniques (HA, nCO-VMAT and CK) can minimize the irradiated doses to normal brain tissues and achieve satisfying CI and GI. The beam delivery time required for HA is shorter, but the beam delivery time required for CK is much longer.
Last Update: 2022-11-25