Abstract

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Author(s):: WEI Xiaping1; SU Jiehong1; HUANG Xiaowei2; WANG Xiaoshen3; WANG Xingliu3; ZHANG Zhen3; LIU Yeming1; HUANG Mingchao1; 1. Department of Radiation Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510080, China 2. Science and Technology Division, Dongguan University of Technology, Dongguan 523808, China 3. Varian Medical Systems, Beijing 100176, China

Keywords:: Keywords: breast cancer Halcyon intensity-modulated radiotherapy treatment planning

Abstract:: Abstract: Objective To reduce the difficulty of intensity-modulated radiotherapy (IMRT) planning for breast cancer by exploring a simple and rapid method for breast cancer IMRT planning based on Halcyon platform. Methods Ten cases of breast cancer with supraclavicular target were retrospectively selected. Fixed-mode 12-field IMRT planning was carried out on Halcyon, and the specific auxiliary structure was delineated. Halcyon-based IMRT plan (HAL_IMRT) of breast cancer was obtained after the optimization using basically fixed optimization objectives. The obtained plan was compared with the conventional TrueBeam VMAT plan in clinic (TrueBeam_VMAT). Results The [V5], [V10], [V20] and [Dmean] of ipsilateral lung, the [V5 of ]contralateral lung and [the V5] and [Dmean] of contralateral breast in HAL_IMRT plan were significantly lower than those in TrueBeam_VMAT plan (P<0.05). There were no significant differences in CI, HI, [D2] and [D98 ]of target area (P>0.05), but the maximum point dose ([Dmax]) of target area in HAL_IMRT plan was higher than that of TrueBeam_VMAT plan (P<0.05). Conclusion When meeting clinical dose requirements, fixed-mode HAL_IMRT planning can reduce the dose to organs-at-risk and significantly reduce the difficulty of IMRT planning for breast cancer.