Evaluation of Auto-Planning technique-based volumetric modulated arc therapy plan for lung cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第8期
- Page:
- 925-928
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Evaluation of Auto-Planning technique-based volumetric modulated arc therapy plan for lung cancer
- Author(s):
- LI Huijun; WANG Linjing; WANG Ruihao; ZHOU Lu; PENG Yingying; LIAO Yuliang; ZHANG Shuxu
- Radiation Therapy Center, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, China
- Keywords:
- Keywords: Auto-Planning lung cancer volumetric modulated arc therapy dosimetry
- PACS:
- R734.2；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.08.001
- Abstract:
- Abstract: Objective To compare the dosimetry differences between the Auto-Planning technique-based volumetric modulated arc therapy (AP-VMAT) plan and the conventional VMAT plan manually designed by the physicist (M-VMAT) for lung cancer, thereby exploring the optimization performance and clinical application value of Auto-Planning technique in VMAT planning for lung cancer. Methods Twenty-five patients with lung cancer who had completed radiotherapy were randomly selected.Two kinds of VMAT plans, namely AP-VMAT plan and M-VMAT plan, were designed for each patient. AP-VMAT plans were automatically generated by Pinnacle3 V9.10 system, while M-VMAT plans were manually designed. The dose distribution of the target area and organs-at-risk sparing were analyzed and compared between two groups of plans. Results The dose coverage of the target area and limit of organs-at-risk met the clinical requirements in both groups. The maximum dose to the target area in AP-VMAT plan was slightly higher than that in M-VMAT plan, but the conformity index in AP-VMAT plan was significantly better. Compared with M-VMAT plan, AP-VMAT plan effectively reduced the maximum dose and mean dose received by spinal cord, decreased the V30 and mean dose in both lungs and the V40, V30 and mean dose in heart, and the differences were statistically significant (P<0.05). Conclusion AP-VMAT plan meets the clinical requirements for lung cancer.Compared with M-VMAT plan, AP-VMAT plan has better target dose distribution and reduces the doses to spinal cord, lungs and heart, protecting normal tissues better.
Last Update: 2022-09-05