Differentiating adult intracranial medulloblastoma and ependymoma using MRI signs and ADC(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第10期
- Page:
- 1244-1249
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Differentiating adult intracranial medulloblastoma and ependymoma using MRI signs and ADC
- Author(s):
- XUE Caiqiang1; 2; 3; 4; LI Shenglin1; 2; 3; 4; LIU Xianwang1; 2; 3; 4; DENG Juan1; 2; 3; 4; ZHOU Junlin1; 2; 3; 4
- 1. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730030, China 2. The Second Clinical Medical School, Lanzhou University, Lanzhou 730030, China 3. Key Laboratory of Medical Imaging of Gansu Province, Lanzhou 730030, China 4. Gansu International Scientific and Technological Cooperation Base of Medical Imaging Artificial Intelligence, Lanzhou 730030, China
- Keywords:
- Keywords: medulloblastoma ependymoma magnetic resonance imaging apparent diffusion coefficient
- PACS:
- R739.41；R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.10.011
- Abstract:
- Abstract: Objective To explore the value of MRI signs and apparent diffusion coefficient (ADC) in differentiating adult intracranial medulloblastoma from ependymoma. Methods The clinical, MRI and pathological data of 16 adults with intracranial medulloblastoma and 24 with ependymoma confirmed by surgery and pathology were retrospectively analyzed.The differences between two groups in MRI signs and ADC values ?#8203were compared, and receiver operating characteristic curve was used to assess the diagnostic efficacy of ADC values in the differentiation of adult intracranial medulloblastoma and ependymoma. Results There were statistically significant differences between adult medulloblastoma and ependymoma in age, tumor location and degree of enhancement (P<0.05), but not in gender, morphology, tumor boundary, cystic degeneration, peritumoral edema, maximum diameter of the tumor, and maximum diameter of edema (P>0.05). The ADCmean, ADCmin and rADC values ?#8203of adult ependymoma were greater than those of adult medulloblastoma, and the differences were statistically significant (P<0.05). When the ADCmean threshold was 665.00 mm2/s, it had the best performance for the differential diagnosis of adult medulloblastoma and ependymoma, with an AUC of 0.966, and its sensitivity and specificity were 0.958 and 0.937, respectively. Conclusion The combination of MRI signs and ADC has important clinical value for the preoperative differentiation of adult medulloblastoma and ependymoma, and it is helpful to assist the formulation of preoperative personalized diagnosis and treatment scheme.
Last Update: 2022-10-27