Relationship between carotid plaques burden and stroke: an evaluation by high-resolution craniocervical MR vessel wall imaging(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第3期
- Page:
- 328-332
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Relationship between carotid plaques burden and stroke: an evaluation by high-resolution craniocervical MR vessel wall imaging
- Author(s):
- LI Yaozhi; XIE Yicai
- Department of Radiology, Wuzhou Red Cross Hospital, Wuzhou 543002, China
- Keywords:
- Keywords: magnetic resonance imaging craniocervical integration vessel wall imaging carotid plaques burden stroke predictive value
- PACS:
- R445.2；R743.9
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.03.012
- Abstract:
- Abstract: Objective To explore the relationship between carotid plaques burden and stroke by high-resolution craniocervical MR vessel wall imaging (HR-VWI). Methods A total of 100 patients with ischemic stroke were enrolled as study group, and another 50 asymptomatic patients at high risk as control group. All subjects underwent MRI plain scan and enhanced HR-VWI. Carotid wall parameters, including lumen area (LA), total vascular area (TVA), wall area (WA), normalized wall index (NWI), were measured on the ischemic and non-ischemic sides. According to whether there was irreversible death of brain tissues, patients in study group were further divided into good prognosis group and poor prognosis group, and the carotid wall parameters on ischemic side were compared between the two groups for analyzing their evaluation value for prognosis. The correlation between carotid wall parameters and score of National Institutes of Health Stroke Scale (NIHSS) was also analyzed. The patients in control group were followed-up for 2 years, and then further grouped into stroke group and normal group according to whether they had a stroke. The carotid wall parameters were compared between stroke group and normal group for analyzing their predictive value for ischemic stroke. Results In study group, the TVA, WA and NWI on ischemic side were greater than those on non-ischemic side, while LA was lower than that on non-ischemic side (P<0.05). The TVA, WA and NWI in poor prognosis group were greater than those in good prognosis group, while LA was lower than that in good prognosis group (P<0.05). The AUC of the combination of carotid wall parameters for assessing prognosis was greater than 0.75. LA was negatively correlated with NIHSS score (P<0.05), but TVA, WA and NWI were not correlated with NIHSS score (P>0.05). Compared with normal group, stroke group had larger TVA, WA and NWI, but lower LA (P<0.05). The AUC of the combination of carotid wall parameters for assessing the onset of ischemic stroke in high-risk groups was greater than 0.75. Conclusion The combination of TVA, WA, NWI and LA is of evaluation value for the prognosis of patients with ischemic stroke, and is of predictive value for stroke onset in high-risk groups. Moreover, LA is related to the severity of neurological damage.
Last Update: 2022-03-28