Quantitative evaluation of the quality of intensity-modulated radiotherapy plan for nasopharyngeal carcinoma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第10期
- Page:
- 1196-1202
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Quantitative evaluation of the quality of intensity-modulated radiotherapy plan for nasopharyngeal carcinoma
- Author(s):
- GU Huikuan1; 2; CHEN Li2; HU Jiang2; DENG Xiaowu2; ZHOU Linghong1
- 1. School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China 2. Department of Radiation Oncology, Sun Yat-sen University Cancer Center/State Key Laboratory of Oncology in South China/Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China
- Keywords:
- Keywords:?asopharyngeal carcinoma intensity-modulated radiotherapy plan quality index quantitative evaluation method
- PACS:
- R811
- DOI:
- DOI:10.3969/j.issn.1005-202X.2021.10.003
- Abstract:
- Abstract:?bjective?o study the feasibility of a method for quantitatively evaluating the quality of radiotherapy plan for nasopharyngeal carcinoma.?ethods Based on the dose requirements of the RTOG 0615 clinical trial and the combination with clinical needs of Sun Yat-sen University Cancer Center, a model for quantitatively evaluating the quality of radiotherapy plans for nasopharyngeal?arcinoma?as designed, and the plan quality index (PQI) of each plan was calculated. A total of 123 cases of nasopharyngeal carcinoma treated with radiotherapy were analyzed in the study. The sensitivity of the quantitative evaluation method to the prescription dose change was evaluated by adjusting the prescribed dose (±3%) of clinical plan and calculating PQI. Meanwhile, according to the existing 30 clinical plans, the calculation results obtained by the proposed evaluation method were compared with the plans selected by clinicians to verify the consistency of the evaluation method and the clinicians decision. Results The PQI of 3 groups of plans, namely +3% prescribed dose, -3% prescribed dose and the original treatment plan, were 68.27±9.84, 63.93±12.78, 79.33±12.40, respectively and the differences between these groups were statistically significant (P<0.01). For the 30 clinical plans, the PQI of the plans selected by physicians was 80.15±10.96, while that of the unselected plans was 74.78±9.41 (P<0.01). The consistency between the results of the evaluation algorithm and the plan selected by clinicians was 83.3%. Conclusion?he proposed method can be used for the quantitative evaluation of the clinical plan quality for it is sensitive to the prescribed dose and has high consistency with the selection made by clinicians.
Last Update: 2021-10-28