Abstract

Info

Author(s):: ZHANG Bailin1; Huang Zeyu2; DAI Zhenhui1; ZHU Lin1; YANG Geng1; JIN Huaizhi1; GAO Lei1; WANG Xuetao1; 1. Department of Radiotherapy in Guangzhou Higher Education Mega Center, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China 2. School of Medical Information Engineering, Guangzhou University of Chinese Medicine, Guangzhou 510006, China

Keywords:: Keywords: radiomics rectum rectal filling rectal wall computed tomography

Abstract:: Objective To investigate the effects of rectal filling on the CT radiomics features of rectal wall. Methods The positioning CT images of 95 patients treated by brachytherapy for cervical cancer were collected. CT scans were performed before and after rectal filling with KUSHEN Ningjiaos, and the rectal wall was manually delineated. A total of 851 features in 7 categories were calculated and extracted, including morphology, first order statistical feature, grey level dependence matrix, grey level run length matrix, gray level co-occurrence matrix, grey level size zone matrix and neighborhood grey-tone difference matrix. The stability of features was evaluated using concordance correlation coefficient (CCC), and the effects of rectal filling on the CT radiomics features of rectal wall was analyzed by Wilcoxon signed rank test. Results The comparison before and after rectal filling revealed that 13% (113/851) of the features remained stable (CCC<0.8), and that features with significant difference (P<0.05) accounted for 92% (782/851). Conclusion The rectal filling which has a great effect on the CT radiomics features of rectal wall should be of concern.