Measurement of pulmonary ventilation in elderly patients with esophageal cancer by 4DCT(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第3期
- Page:
- 277-280
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Measurement of pulmonary ventilation in elderly patients with esophageal cancer by 4DCT
- Author(s):
- SHEN Jianjun; NIU Weina; YAN Bing; YU Xiao; XIE Yuan
- Department of Radiation Oncology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China
- Keywords:
- Keywords: esophageal cancer four-dimensional computed tomography radiotherapy pulmonary function
- PACS:
- R459.2；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2021.03.002
- Abstract:
- Abstract: Objective To use four-dimensional computed tomography (4DCT) for evaluating the pulmonary ventilation in esophageal cancer patients aged 75 years and over. Methods Thirty-one esophageal cancer patients aged 75 years and over were enrolled in the study. 4DCT images were dichotomized by geometry after deformation. The pulmonary ventilation function was evaluated by 3 indexes, namely superior-inferior pulmonary ventilation ratio, left-right pulmonary ventilation ratio and anterior-posterior pulmonary ventilation ratio. Results There was significant difference between chronic obstructive pulmonary disease (COPD) group and non-COPD group in superior-inferior pulmonary ventilation ratio (P<0.05), but not in anterior-posterior pulmonary ventilation ratio and left-right pulmonary ventilation ratio. Moreover, significant difference was only found in superior-inferior pulmonary ventilation ratio between patients aged 75-80 years and those aged 80 years and over (P<0.05). After radiotherapy, there were significant differences between COPD group and non-COPD group in superior-inferior pulmonary ventilation ratio (P<0.05) and anterior-posterior pulmonary ventilation ratio (P<0.05), and the superior-inferior pulmonary ventilation ratio in patients aged 75-80 years was significantly different from that in those aged 80 years and over (P<0.05). During radiotherapy, the pulmonary ventilation function in chemoradiotherapy group was similar to that in non-concurrent chemotherapy group. Conclusion 4DCT can be used to detect the variations of pulmonary ventilation function before and after radiotherapy, providing the possibility for the early clinical intervention.
Last Update: 2021-03-30