Dosimetric comparison of IMRT optimization with dose volume optimizer versus photon optimizer in pediatric craniospinal irradiation(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第12期
- Page:
- 1460-1465
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric comparison of IMRT optimization with dose volume optimizer versus photon optimizer in pediatric craniospinal irradiation
- Author(s):
- ZHANG Ping1; DENG Guanhua1; DAI Peng1; LUO Rishun1; LUO Longhui1; HUANG Qing2
- 1. Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou 510510, China 2. Department of Equipment, Guangdong Sanjiu Brain Hospital, Guangzhou 510510, China
- Keywords:
- Keywords: pediatric tumor intensity-modulated radiotherapy dose volume optimizer algorithm photon optimizer algorithm craniospinal irradiation
- PACS:
- R815.6；R312
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.12.002
- Abstract:
- Abstract: Objective To investigate the dosimetric characteristics between dose volume optimizer (DVO) algorithm and photon optimizer (PO) algorithm in pediatric craniospinal irradiation using intensity-modulated radiotherapy (IMRT). Methods DVO algorithm and PO algorithm were used to generate DVO plans and PO plans for 15 patients who received craniospinal irradiation using IMRT in Guangdong Sanjiu Brain Hospital from July 2018 to January 2020. The dosimetric characteristics, optimization efficiency and monitor units of DVO plans and PO plans were evaluated. Results There was no significant difference between PO plans and DVO plans in D2%, D98%, homogeneity index and gradient index of PTV (P>0.05). However, compared with PO plans, DVO plans showed better D50% and conformity index (CI) of PTV (P<0.05), and smaller volume of cervical PTV receiving lower than 95% of the prescription dose (P<0.05). The doses received by the lungs, right kidney and heart in DVO plans were lower than those in PO plans (P<0.05), whereas the doses received by the other organs-at-risk did not differ significantly between DVO plans and PO plans (P>0.05). Compared with those in PO plans, the monitor units in DVO plans was increased by an average of 63 MU, and the optimization time was increased by an average of 224 s. Conclusion The application of DVO algorithm in pediatric craniospinal irradiation using IMRT can improve the target conformity, reduce the volume of cervical PTV receiving lower than 95% of the prescription dose, and may lower the incidence of tumor recurrence. Therefore, DVO algorithm is recommended for IMRT optimization in pediatric craniospinal irradiation.
Last Update: 2022-12-23