Application of low-dose multidetector CT scan and high-resolution reconstruction in COVID-19 pneumonia screening(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第4期
- Page:
- 456-460
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application of low-dose multidetector CT scan and high-resolution reconstruction in COVID-19 pneumonia screening
- Author(s):
- WANG Yannan1; 2; 3; ZHOU Junlin2; 3; LIU Jianli2; 3; NA Feiyang4; ZHOU Sheng1; 5
- 1. First Clinical Medical School, Gansu University of Chinese Medicine, Lanzhou 730000, China 2. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730000, China 3. Key Laboratory of Medical Imaging in Gansu Province, Lanzhou 730000, China 4. Allergy Department, Gansu Provincial Maternity and Child-care Hospital, Lanzhou 730000, China 5. Department of Radiology, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730000, China
- Keywords:
- Keywords: multidetector computed tomography low-dose high-resolution reconstruction COVID-19 pneumonia
- PACS:
- R563.1；R816.4
- DOI:
- DOI:10.3969/j.issn.1005-202X.2021.04.012
- Abstract:
- Abstract: Objective To explore the application value of low-dose multidetector computed tomography (CT) scan combined with high-resolution reconstruction in the screening of COVID-19 pneumonia. Methods A total of 66 patients with suspected COVID-19 pneumonia who came to Lanzhou University Second Hospital from February 1, 2020 to March 1, 2020 were enrolled, and then randomly divided into 2 groups, namely conventional-dose CT scan group (n=33, 120 kV, 300 mAs) and low-dose CT scan group (n=33, 100 kV, 70 mAs). A 512×512 matrix was adopted in conventional-dose group, and a 1 024×1 024 matrix in low-dose group. Meanwhile, low-dose group was processed with 4 iterative algorithms with different weights (30%, 50%, 70%, 90%). The radiation dose and image quality of two groups were compared. Results The effective radiation dose of low-dose group was (1.81±0.14) mSV, which was reduced by 73.5% (P<0.05) compared with (6.83±0.68) mSV in conventional-dose group. The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of low-dose group with a 1 024×1 024 matrix and 90% weight iterative algorithm were slightly lower than those of conventional-dose group with a 512×512 matrix and 90% weight iterative algorithm, without statistical differences (SNR: 5.11±0.75 vs 5.38±0.41, CNR: 5.37±0.33 vs 5.44±0.51, P>0.05). The subjective image quality scores of pulmonary window and mediastinal window in low-dose group were lower than those in conventional-dose group, but the differences were not statistically significant (pulmonary window: 3.30±0.72 vs 3.39±0.78 mediastinal window: 3.15±0.90 vs 3.36±0.82, P>0.05). Conclusion Multidetector CT for low-dose scan combined with high-resolution reconstruction technique and 90% weight iterative algorithm can be applied for COVID-19 pneumonia screening, which can significantly reduce the radiation dose to patients while ensuring image quality.
Last Update: 2021-04-29