Dosimetric study on non-coplanar volumetric modulated arc therapy technique in breast and clavicular radiotherapy following breast-conserving surgery for left-sided breast cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第6期
- Page:
- 691-695
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric study on non-coplanar volumetric modulated arc therapy technique in breast and clavicular radiotherapy following breast-conserving surgery for left-sided breast cancer
- Author(s):
- LI Cong; LI Sihan; XIA Bing
- Department of Radiation Oncology, the First Hospital of China Medical University, Shenyang 110001, China
- Keywords:
- Keywords: left-sided breast cancer breast-conserving surgery non-coplanar volumetric modulated arc therapy dosimetry
- PACS:
- R811.1；R730.55
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.06.007
- Abstract:
- Abstract: Objective To investigate the dosimetric differences between non-coplanar volumetric modulated arc therapy (nVMAT) and VMAT in breast and clavicular radiotherapy following breast-conserving surgery for left-sided breast cancer. Methods The clinical VMAT plans of 10 patients undergoing breast-conserving surgery for left-sided breast cancer were re-planned using non-coplanar VMAT technique. The dosimetric parameters of target areas and organs-at-risk were compared. The comparison indicators of organs-at-risk included the Dmean of heart, lungs and contralateral breast, the Dmax of spinal cord and coronary artery, the V20, V30 of heart, the V5, V20 of the left lung and the V30, V40 of trachea. Results nVMAT plan was superior to VMAT plan in the homogeneity index of P-CTV, the Dmean of heart, lungs and contralateral breast, and the Dmax of coronary artery, with statistical differences (P<0.05). Compared with those in VMAT plan, the conformity indexes of P-CTV and P-GTV, and the V30 of heart, the V30 of left lung, the V30, V40 of trachea in nVMAT plan were slightly better, but there was no statistical difference (P>0.05). Moreover, the number of motion units in nVMAT plan was significantly increased (P<0.05). Although the Dmax of the spinal cord was increased in nVMAT plan, the difference between two plans was trivial (P>0.05). Conclusion nVMAT technique can increase the homogeneity index of target volumes and improve organs-at-risk sparing, especially reducing the Dmean of heart and the Dmax of coronary artery.
Last Update: 2020-07-03