Dosimetric differences between Acuros external beam algorithm and anisotropy analysis algorithm in volumetric modulated arc therapy for lung cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第6期
- Page:
- 676-679
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric differences between Acuros external beam algorithm and anisotropy analysis algorithm in volumetric modulated arc therapy for lung cancer
- Author(s):
- XU Shilei1; ZHANG Jiutang1; ZHANG Junjun2; CHEN Ni1
- 1. Department of Radiation Physics and Technology, Hunan Cancer Hospital, Changsha 410013, China 2. Department of Radiation Oncology, the Third Xiangya Hospital of Central South University, Changsha 410013, China
- Keywords:
- Keywords: lung cancer Acuros external beam algorithm anisotropic analytical algorithm volumetric modulated arc therapy
- PACS:
- R811.1；R734.2
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.06.004
- Abstract:
- Abstract: Objective To compare the dosimetric differences in the volumetric modulated arc therapy (VMAT) plans using Acuros external beam (AXB) algorithm versus anisotropy analysis algorithm (AAA) for the treatment of lung cancer. Methods Twenty patients with lung cancer were randomly selected. After the CT images were imported into the planning system, target areas and organs-at-risk (OAR) were delineated, and the VMAT with two arcs was designed for each patient. The two algorithms were used to calculate the dosimetric distributions in target areas and the doses to organs-at-risk (OAR) such as lungs, heart and spinal cord, and the results calculated by AXB algorithm were compared with those calculated by AAA. Results For planning gross target volume, there was no significant difference between AXB algorithm and AAA in the calculation of minimum dose (P>0.05), but the maximum dose and mean dose calculated by AXB algorithm were lower than those calculated by AAA (P<0.05). For planning target volume, there was no significant difference between two algorithms in the calculation of maximum dose and minimum dose (P>0.05), but the mean dose calculated by AXB algorithm was lower than that calculated by AAA (P<0.05). Moreover, AXB algorithm was superior to AAA in conformity index and homogeneity index (P<0.05). The maximum dose of spinal cord, the V30, V40 and mean dose of the heart, and the V5, V20 and mean dose of the lungs which were calculated by AXB algorithm were lower than those obtained by AAA (P<0.05). Conclusion Both AAA and AXB algorithm can satisfy the clinical requirements, but compared with AAA, AXB algorithm is more accurate, especially for low-density areas like the lungs.
Last Update: 2020-07-03