Abstract

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Title:: Value of magnetic resonance perfusion imaging in the differential diagnosis of high-grade glioma and single brain metastasis

Author(s):: LIU Sheng; Department of Radiology, Guilin People’s Hospital, Guilin 541002, China

Keywords:: Keywords: magnetic resonance perfusion imaging; high-grade glioma; single brain metastasis; differential diagnosis

Abstract:: Abstract: Objective To study and evaluate the diagnostic value of magnetic resonance perfusion imaging in high- grade glioma. Methods A total of 84 patients with pathologically confirmed high-grade glioma and 60 patients with single brain metastasis were enrolled in the study. Dynamic contrast- enhanced magnetic resonance perfusion imaging was used to measure the relative cerebral blood volume (rCBV) in tumor parenchyma and peritumor edema area, and a statistical analysis was conducted on the obtained data. Results The time-signal intensity curve of high-grade glioma was different from that of single brain metastasis. In tumor parenchyma, the rCBV of single brain metastasis was lower than that of high-grade glioma, with statistical significance (4.03±0.79 vs 5.48±1.32, P<0.05). In the edema area, the rCBV of single brain metastasis was 0.74±0.35, lower than 1.48±0.26 of high-grade glioma, and the difference was statistically significant (P<0.05). Conclusion Dynamic contrast-enhanced magnetic resonance perfusion imaging has a high clinical value in the differential diagnosis of single brain metastasis and high-grade glioma.