Abstract

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Title:: Application value of three-dimensional arterial spin labeling technique in grade 1 hypertensive cerebral perfusion

Author(s):: CHEN Shanshan1; GAO Langlang2; LIU Haitao3; DU Fang4; HOU Weihuan2; ZHAO Haitao2; WEI Mengqi2; 1. Department of Ultrasonography, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 2. Department of Radiology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 3. Department of Cardiology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 4. Department of Neurology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China

Keywords:: ; Keywords: three-dimensional arterial spin labeling perfusion imaging; hypertensive encephalopathy; cerebral blood flow

Abstract:: Abstract: Objective To quantitatively analyze the application of three-dimensional arterial spin labeling (3D ASL) perfusion imaging in patients with grade 1 hypertension and investigate its application value. Methods A total of 36 patients with grade 1 hypertension and 14 non-hypertension health controls were examined by routine magnetic resonance imaging and 3D ASL perfusion imaging. The local cerebral blood flow (CBF) values of 17 specific brain regions in two groups were measured to reflect the cerebral hemodynamic parameters, thereby comparing the differences of perfusion parameters in various regions. Results The CBF values of lentiform nucleus, thalamus, superior frontal gyrus, cingulate gyrus, inferior frontal gyrus, middle frontal gyrus, centrum semiovale, anterior central gyrus, posterior central gyrus, temporal lobe and occipital lobe in grade 1 hypertension group were lower than those in control group, with statistical differences (P<0.05). The CBF values of caudate nucleus, amygdaloid nucleus, anterior and posterior horns of lateral ventricle and corpus callosum were similar in grade 1 hypertension group and control group, without significant differences (P>0.05). Conclusion 3D ASL technique can be used to detect abnormal cerebral perfusion in patients with grade 1 hypertension, which is of great value in the prevention and treatment of hypertensive encephalopathy.