Abstract

Info

Title:: Progress in basic research on stem cells and its clinical application prospects

Author(s):: LI Ting1; CHEN Lizhi1; HUANG Wenhua1; 2; 1. National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China; 2. Guangdong Province Medical 3D Printing Application Transformation Engineering Technology Research Center, Guangzhou 510515, China

Keywords:: Keywords: stem cell; basic scientific research; clinical treatment; isolation and purification; proliferation potential; review

Abstract:: Abstract: Stem cells, a kind of primitive cell population with strong ability of renewal, replication, proliferation and differentiation, are mainly divided into two categories, namely embryonic stem cells and adult stem cells. In recent years, with the further in-depth research on cells, several kinds of cells, including hematopoietic stem cells, mesenchymal stem cells and neural stem cells, have become valuable research topics in biomedical sciences. Because of the continuous development of stem cell isolation, extraction, purification technologies and the unique biological characteristics of stem cells, the application of stem cells in tissue repair and regenerative medicine has achieved breakthrough progresses, and they play an important role in clinical treatment. In addition, stem cells play a major role in drug development, molecular imaging, and 3D scaffolds. Herein the roles of stem cells in basic scientific research and clinical treatment are reviewed, so as to provide references for the further research on stem cell therapy and the development of techniques in stem cell research.